Wednesday, May 15, 2013

Tony Mckenna: Bitcoin: A Brave New World

Since the mid-'90s the Internet has revolutionized the world. I am old enough to remember the place before. A place in which children used to send thank-you notes for birthday presents by post, where you would need to go out to rent a film from the local video store, or make a trip to a news stand in order to pick up a paper which contained yesterday's news.

But the Internet opened up a new type of world; a virtual one where you can send emails without needing to step outside and post a letter; where you can find out how your friends are via Twitter feeds or Facebook updates -- avoiding the rigmarole of actually knocking on a door and asking; where relationships and even marriages are realized online without the participants ever even meeting in 'real' life.

In fact -- across cyber space whole communities are formed -- manifested in and through digital cities where avatars enjoy virtual lives, travel to virtual workplaces, create virtual families and even endure virtual deaths. In the limitless void of the e-ther, every real world action receives its ghostly cybernetic echo, generating a strange and wonderful realm through the looking glass of your own computer terminal.

But what if the boundaries between the virtual space and the real one began to dissolve? What if things from the one realm started to cross over into the other?

If your knee jerk reaction is to think that sounds like the fantastical stuff of science fiction then I urge you to think again. It is closer than you think! Ladies and gentleman (roll of the drum)... take a look at Bitcoin!

Bitcoin is a form of virtual currency. Nothing new or particularly remarkable in that, mind you, as for ages computer geeks have been creatively designing their own forms of virtual currency in order to pay for virtual products - players using pixelated doubloons to acquire digital weaponry for on-line medieval role-playing games, for instance. But what is unique about Bitcoin -- is that it is the first peer-to-peer virtual currency which can also be used to buy actual real world products. Since its inception in 2008, Bitcoin has proved more and more viable; it is increasingly accepted by merchants and individuals across the world, and even a few major companies such as WikiLeaks.

As it operates peer-to-peer, Bitcoin effectively cuts out the middle man. Under this model
you could send a transfer of money from Boston to London without a portion of it going to your bank or an organization like Western Union. The transaction provides an unmediated link between sender and receiver. Over time they would save a great deal of money. And all that is required is an Internet IP address.

But this lack of regulation, say its critics, means that Bitcoin is open to all forms of abuse. Already it has been linked to 'deep web' black market sites -- sites like the infamous Silk Road which allows buyers to anonymously order various hard drugs while maintaining user anonymity. A crypto-currency like Bitcoin which need not pass through any bank accounts is conducive to invisibility.

The FBI have speculated, should Bitcoin continue to grow, it 'might logically attract money launderers, human traffickers, terrorists, and other criminals who avoid traditional financial systems.' In addition, should the currency depreciate as a result of sudden crisis, there is no central bank or state-sponsored support its users might rely on to help it to stabilize. Indeed there were ominous signs of this when in 2011, and again this April, the Bitcoin 'bubble' seemed to burst and a panic sell-off ensued which caused Bitcoin to lose its liquidity.

Its advocates are more optimistic, however. Mihai Alisie, editor of Bitcoin Magazine, acknowledges that criminal elements may try to take advantage of Bitcoin, but argues this is no different from any other product -- 'You have a knife, and with that knife you can put butter on your bread or you can kill someone. But you make the tool bad or good.'

And the argument which suggests any major currency must require some form of central banking organization is inevitably damaged by the nature of the current economic crisis -- which was very much bank driven. Most recently the crisis has claimed its latest victim -- Cyprus. The president there made the controversial announcement that the bailout for the country's banks would, in part, be paid for by seizing money from the accounts of depositors -- and when this was rejected by the parliament, a levy was placed on substantial deposits, while withdrawals were limited along with overseas transfers.

The sense of not having power over their own money caused a great number of Cypriots to start buying up bitcoins as a means of better controlling their finances. As a consequence, Cyprus will soon become the first place in the world to feature a Bitcoin ATM machine.

Nevertheless, in light of its sudden economic depreciation this year, many critics suggest that Bitcoin is in terminal decline. And they might well be right. But this also misses the point. What is most significant about Bitcoin is the idea of it. True, this particular incarnation may well cease to exist in the near future. But money has never stopped evolving -- from its early forms where crops like barley were used as currency, or sea shells, to later variations which lead to metal coinage and then paper notes and checks.

The idea of a peer-to-peer virtual currency floated across vast swathes of international populations irrespective of borders could well be the next stage in the evolution of money -- its brave new world.

?

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Source: http://www.huffingtonpost.com/tony-mckenna/bitcoin-currency_b_3267952.html

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Dr. Joyce Brothers Passes Away At 85 (VIDEO)

Dr. Joyce Brothers Passes Away At 85 (VIDEO)

Dr Joyce Brothers dead at 85Dr. Joyce Brothers, a columnist, psychologist, and television personality, has died at the age of 85. The adorable star was very popular on television, where she answered questions about relationships and even sex in a charming way. Dr. Joyce Brothers is credited with being the first of television advice shows, being labeled the mother of ...

Dr. Joyce Brothers Passes Away At 85 (VIDEO) Stupid Celebrities Gossip Stupid Celebrities Gossip News

Source: http://stupidcelebrities.net/2013/05/dr-joyce-brothers-passes-away-at-85-video/

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Rushmore.fm Wants To Fix The Music Industry, Ex-Virgin Group Online Boss Named As CEO

ced1d69634815ccfedf8c20195a33c037b20d8b96dRushmore.fm, a new London-based startup founded by Fictive Kin and Betaworks, is de-cloaking somewhat today with what sounds like the rather lofty but noble mission to fix the music industry. Described as a "music ecosystem", the (currently) invite-only site initially consists of a Wikipedia-like music resource where you're encouraged to contribute and follow content, although the site's broader aim is to connect music fans "directly and effortlessly with the artists and labels they love", and in doing so make it easier to make a living from music.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/4ZVEsRcAXlY/

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What Can We Build with All the Lego Bricks in the World?

Since 1958, 472 billion Lego bricks have been made. And even though most of those bricks are hardly bigger than your finger, 472 billion of anything is a ridiculous number. So what could you build with all the Lego bricks in the world? Surprisingly a lot. Like 74 Empire State buildings a lot.

There really needs to be more huge Lego structures in the world. Hell, there just needs to be more Lego in everyones life.

Imagine it, if 50,000 Lego bricks could create a 104-foot tall Lego Tower, 472 billion could practically build you a spaceship. Or a bridge to space. Of course, the Lego bridge might just end up crushing itself but hey, whatever, more Lego is always good.

[Movoto via DesignTAXI]

Source: http://gizmodo.com/what-can-we-build-with-all-the-lego-bricks-in-the-world-505033576

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Monday, May 13, 2013

US retail sales rise in April on cars, clothing

(AP) ? Americans increased their spending in April at retail businesses, buying more cars and clothes while paying less for gas. The rebound from a weak March suggests consumers may help boost economic growth again this spring.

Retail sales edged up 0.1 percent in April from March, the Commerce Department said Monday. That's an improvement from a 0.5 percent decline in March, which was the largest drop in nine months.

The April gain was stronger when taking out the effect of lower gas prices, which reduced sales at gas stations 4.7 percent ? the largest decline since December 2008. The retail sales report is not adjusted for price changes.

When excluding gas station sales, retail spending rose 0.7 percent. And core retail sales, exclude gas, autos and building supplies, increased 0.5 percent. Economists pay close attention to core sales because they strip out the most volatile categories.

Sales of autos rose 1 percent in April, rebounding from a 0.6 percent drop in March. Sales at clothing stores increased 1.2 percent and sales at general merchandise stores, a category that covers department stores, rose 1 percent. Sales were also strong at building materials and garden supply stores and electronics and appliance stores.

Consumers increased their spending in April, despite paying higher Social Security taxes that has reduced their paychecks this year. Their spending will likely add to economic growth in the April-June quarter. Consumer spending makes up roughly 70 percent of economic activity.

"This is a good start to the second quarter," said Jennifer Lee, senior economist at BMO Capital Markets. "The rest of the year is expected to rise further on stronger household finances."

The economy grew at a 2.5 percent annual rate from January through March, up from a 0.4 percent rate in the October-December quarter of 2012. The gain was largely because of the fastest growth in consumer spending in more than two years.

But most of the increase came from greater spending at the start of the quarter. Consumers cut back sharply on retail spending in March, while paying more for utilities to heat their homes during a colder-than-usual month.

Some economists worried that the weak month of spending in March was a sign that the tax increase was starting to catch up with the consumer.

But other factors appear to have made the consumer more resilient.

Steady job growth helped offset some of the pain from the tax increase. The economy added 165,000 jobs in April. And it has created an average of 208,000 jobs a month since November. That's well above the monthly average of 138,000 for the previous six months.

Cheaper gas is leaving consumers with more disposable income. The national average price has risen slightly over the past week to $3.58 a gallon. But it is still 21 cents lower than the peak price reached on Feb. 27.

And a surging stock market and increases in home prices may be making consumers feel wealthier and more inclined to spend.

The economy is benefiting from the Federal Reserve's aggressive stimulus actions, which have lowered borrowing costs for consumers and businesses and helped lift the stock market to record highs. The Fed has said it plans to keep short-term interest rates at record lows at least until unemployment falls to 6.5 percent.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-05-13-Retail%20Sales/id-2aa87cd78479468e886472780f2a5734

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Syria-linked group blamed in Turkey blasts; 43 die

REYHANLI, Turkey (AP) ? In one of the deadliest attacks in Turkey in recent years, two car bombs exploded near the border with Syria on Saturday, killing 43 and wounding 140 others. Turkish officials blamed the attack on a group linked to Syria, and a deputy prime minister called the neighboring country's intelligence service and military "the usual suspects."

The blasts, which were 15 minutes apart and hit the town of Reyhanli's busiest street, raised fears that Turkey could increasingly be drawn into Syria's brutal civil war.

Turkey already hosts Syria's political opposition and rebel commanders, has given shelter to hundreds of thousands of Syrian refugees and in the past retaliated against Syrian shells that landed in Turkey.

Deputy Prime Minister Besir Atalay said the assailants were from Turkey, but were linked to Syria's intelligence service.

"We have to a great extent completed our work toward identifying the assailants," he told reporters. "We have established that the organization and assailants have links to the pro-regime mukhabarat (intelligence) organization."

He did not name the group, but said the aim of the attack was to pit Turks against Syrian refugees in Reyhanli.

Earlier, another deputy prime minister, Bulent Arinc said: "Our thoughts are that their mukhabarat and armed organizations are the usual suspects in planning and the carrying out of such devilish plans," he said.

Arinc said the attacks were still being investigated, but that If it's proven that Syrian was behind the attack, Turkey would "do whatever is necessary," without specifying if that included military action.

One of the car bombs exploded outside the city hall while the other went off outside the post office. Reyhanli, a main hub for Syrian refugees and rebels in Turkey's Hatay province, is just across the border from Syria's Idlib province. Private NTV television, citing unnamed security sources, said the explosions were remote-controlled and that plastic explosives were used.

Images showed people frantically carrying the wounded through the rubble-strewn streets to safety. Black smoke billowed from a tall building.

The explosions came days before Prime Minister Recep Tayyip Erdogan is scheduled to travel to the U.S. for talks, which are expected to be dominated by the situation in Syria. The car bombings also follow allegations by Erdogan the Syrian regime has fired about 200 missiles tipped with chemical weapons.

Syrian mortar rounds have fallen over the border before, but if the blasts turn out to be linked to Syria it would be by far the biggest death toll in Turkey related to its neighbor's civil war.

Syria shares a more than 500-mile (800-kilometer) border with Turkey, which has been a crucial supporter of the Syrian rebel cause. Ankara has allowed its territory to be used as a logistics base and staging center for Syrian insurgents.

Atalay said 43 people were killed and 140 others were wounded in the blasts. There was no immediate information on the identities or nationalities of the victims.

The bombings" will increase the pressure on the U.S. president next week to do something to show support to Turkey when Erdogan visits him in Washington," said Soner Cagaptay, an expert on Turkey at the Washington Institute. "Washington will be forced to take a more pro-active position on Syria, at least in rhetoric, whether or not there is appetite for such a position here."

Salman Shaikh, director of the Brookings Doha Center, said the attack may force Turkey to take action.

"It?should be a defining moment for Turkey," Shaikh said. "It has been supporting the rebels, and there has been strong rhetoric. But this may be a moment where it really has to assert itself ? if it is the Assad regime (behind the bombings), and it is quite conceivable it is."

Turkey's opposition criticized the government's policy on Syria, saying its active support of the rebels had put the country's security at risk.

"Erdogan's discourse of hatred toward Assad and provocations against the administration in Damascus is coming back to us in the form of attacks and provocations," said Devlet Bahceli, chairman of a nationalist opposition party.

The force of Saturday's explosions gutted some buildings, and the charred shells of cars littered the streets.

"Three buildings partly collapsed and became unusable," Talat Karaca, who witnessed the second explosion from his rooftop, told The Associated Press by telephone. "We couldn't approach the scene for a long time because of the blaze."

Khawla Sawah, the medical director of the Union of Syrian Medical Relief Organizations in Reyhanli, said the town's main hospital was full and many of the wounded were taken to the nearby city of Antakya and to a clinic set up by the Syrian medical relief group on Reyhanli's outskirts. The center received 11 wounded, including one Turk and 10 Syrians.

She said some of the injured told her that the cars that exploded had Syrian license plates.

Both Sawah and another witness, Suzan Alhasoglu, said the incident raised tension in Reyhanli with angry youths attacking Syrians cars and other targets.

"The authorities are asking Syrians to stay home and not drive around in Syrian cars," Sawah said. "Syrian doctors at the Reyhanli hospital were asked to go home too."

Turkey's military released a statement condemning the attack and Foreign Minister Ahmet Davutoglu vowed from Berlin that Turkey would act.

"Those who for whatever reason attempt to bring the external chaos into our country will get a response," he said.

The U.S. Embassy in Ankara issued a statement condemning the "murderous attack" in Reyhanli and said Washington "stands with the people and government of Turkey to identify the perpetrators and bring them to justice."

The main Syrian opposition group, the Syrian National Coalition, condemned the attack and said it stands together with the "Turkish government and the friendly Turkish people."

The coalition sees "these heinous terrorist acts as an attempt to take revenge on the Turkish people and punish them for their honorable support for the Syrian people," it said.

The frontier area has seen heavy fighting between rebels and the Syrian regime. In February, a car bomb exploded at a Syrian border crossing with Turkey, just a few kilometers from Reyhanli, killing 14. Turkey's interior minister at the time blamed Syria's intelligence agencies and its army for involvement.

Four Syrians and a Turk are in custody in connection with the Feb. 11 attack at the Bab al-Hawa frontier post. No one has claimed responsibility, but a Syrian opposition faction accused the Syrian government of the bombing, saying it narrowly missed 13 leaders of the group.

In that bombing, most of the victims were Syrians who had been waiting in an area straddling the frontier for processing to enter Turkey.

Tensions also flared between the Syrian regime and Turkey after shells fired from Syria landed on the Turkish side, prompting Germany, the Netherlands and the U.S. to send two batteries of Patriot air defense missiles each to protect their NATO ally.

___

Suzan Fraser reported from Ankara. Associated Press writers Ezgi Akin in Ankara, and Bassem Mroue, Yasmine Sakher and Karin Laub in Beirut contributed to this report.

Source: http://news.yahoo.com/syria-linked-group-blamed-turkey-blasts-43-die-202225997.html

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Sunday, May 12, 2013

Four new genetic risk factors for testicular cancer identified

May 12, 2013 ? A new study looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men today. The findings from this first-of-its-kind meta-analysis were reported online May 12 in Nature Genetics by researchers at the Perelman School of Medicine at the University of Pennsylvania.

The discovery of these genetic variations -- chromosomal "typos," so to speak -- could ultimately help researchers better understand which men are at high risk and allow for early detection or prevention of the disease.

"As we continue to cast a wider net, we identify additional genetic risk factors, which point to new mechanisms for disease," said Katherine L. Nathanson, MD, associate professor in the division of Translational Medicine and Human Genetics within the department of Medicine. "Certain chromosomal regions, what we call loci, are tied into testicular cancer susceptibility, and represent a promising path to stratifying patients into risk groups -- for a disease we know is highly heritable."

Tapping into three genome-wide association studies (GWAS), the researchers, including Peter A. Kanetsky, PhD, MPH, an associate professor in the department of Biostatistics and Epidemiology, analyzed 931 affected individuals and 1,975 controls and confirmed the results in an additional 3,211 men with cancer and 7,591 controls. The meta-analysis revealed that testicular germ cell tumor (TGCT) risk was significantly associated with markers at four loci -- 4q22, 7q22, 16q22.3, and 17q22, none of which have been identified in other cancers. Additionally, these loci pose a higher risk than the vast majority of other loci identified for some common cancers, such as breast and prostate.

This brings the number of genomic regions associated with testicular cancer up to 17 -- including eight new ones reported in another study in this issue of Nature Genetics.

Testicular cancer is relatively rare; however, incidence rates have doubled in the past 40 years. It is also highly heritable. If a man has a father or son with testicular cancer, he has a four-to six-fold higher risk of developing it compared to a man with no family history. That increases to an eight-to 10-fold higher risk if the man has a brother with testicular cancer.

Given this, researchers continue to investigate genetic variants and their association with cancer.

In 2009, Dr. Nathanson and colleagues uncovered variation around two genes -- KITLG and SPRY4 -- found to be associated with an increased risk of testicular cancer. The two variants were the first striking genetic risk factors found for this disease at the time. Since then, several more variants have been discovered, but only through single GWAS studies.

"This analysis is the first to bring several groups of data together to identify loci associated with disease," said Dr. Nathanson, "and represent the power of combining multiple GWAS to better identify genetic risk factors that failed to reach genome-wide significance in single studies."

The team also explains how the variants associated with increased cancer risk are the same genes associated with chromosomal segregation. The variants are also found near genes important for germ cell development. These data strongly supports the notion that testicular cancer is a disorder of germ cell development and maturation.

"TGCT is unique in that many of the loci are very good biological candidates due to their role in male germ cell development," said Dr. Nathanson. "Disruptions in male germ cell development lead to tumorigenesis, and presumably also to infertility. These conditions have been linked before, epidemiologically, and genes implicated in both of our prior studies, but this study reinforces that connection."

This study was supported in part by Intramural Research Program of the National Cancer Institute and the National Institutes of Health grant (R01CA114478).

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/9BSwT38EXEM/130512141208.htm

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